From Asheville - US 25 to US 276. Furman exit is a couple miles past the 25/276 split.
From Atlanta - I-85 North to I-185 to White Horse Road (US25). Go North on 25. When 25 makes a sharp right and turns into 6 lanes, go to the next light and turn right. Go to the next light and turn right again onto US 276. Furman exit is just ahead on right.
From Charlotte - I-85 south to I-385 toward Greenville. Take SC 291 North exit. Stay on 291 until in meets US 276. Then turn right. Furman exit is a couple mile down on right.